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发表于 2020-4-27 19:52:52
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A viewpoint of population immunology and its application on the COVID 19 outbreak.
Firstly, the formation of population immonology should be explored from the establishment of individual immunity. For COVID 19 coronavirus, one of the pre-conditions of individual immunity should be established by the presence of pathogen biodiversity in the host ecosystem. Before the outbreak of the COVID 19 coronavirus, if individuals have been infected by its relatives virus strains, leading to the establishment of immunity, and the sub-populations of relatives coronavirus strains is less pathogenic and epidemic than COVID 19 strains, then the outbreak of the COVID 19 coronavirus can certainly be prevented, as population immunology would be formed before. However, the outbreak of COVID 19 coronavirus is very sudden, showing the invasive strain status in the receptor’s living ecosystem without any biodisersity in virus community.
Then, the pathogenisis of COVID 19 coronavirus is analyzed by the specificity of invasion-host interactions. In almost cases, epidemic disease only infects a proportion of host population, and the other proportion is resistance against the pathogens due to the specificity of invasion-host interaction between population genetics. However, the non-selective infections of COVID 19 coronavirus reveals the deletion of specificity of invation – host interactions between population genetics, further indicating that the previous host species of COVID 19 coronavirus has apparent genetic distance to the human population, so that the valid biochemical substances of immunity is the enzymes synthesized by the allogenetic chromosomes of a wild animal species as compased with human genomes. Consequently, the inoculation of allogenetic enzymes would not be promising.
The absences in the above two pre-conditions reveals that the population immunology formation of COVID 19 coronavirus would not be realistic, so that the isolation remedy of infection receptors is the only reliable measure to resolve the outbreak of COVID 19 coronavirus.
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